Description

Fluoroacetic Acid 2,3-Dihydroxypropyl Ester is a specialized organofluorine compound that serves as a valuable synthetic intermediate and building block in advanced chemical manufacturing. Its bifunctional structure, featuring both a fluoroacetate moiety and a diol group, enables its use in the creation of complex molecules with tailored properties. This ester is particularly relevant for R&D and production within the pharmaceutical, agrochemical, and specialty polymer sectors, where the introduction of fluorine atoms is a key strategy for modulating biological activity and material characteristics.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated backbone for enhanced metabolic stability or bioavailability.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel herbicides, pesticides, and plant growth regulators that leverage fluorine's unique properties.
• Specialty Polymer Modifier: Acts as a monomer or cross-linking agent in the production of fluorinated polymers, imparting specific characteristics like chemical resistance or altered surface energy.
• Biochemical Research: Employed as a probe or substrate in enzymatic studies and metabolic pathway research due to its fluoroacetate group.
• Liquid Crystal & Electronic Materials: Utilized in the synthesis of fluorinated components for advanced display technologies and electronic coatings.
• Custom Synthesis & Contract Manufacturing: A critical building block for fine chemical and custom synthesis houses serving diverse industrial clients.

Basic Information

Product Name	Fluoroacetic Acid 2,3-Dihydroxypropyl Ester
CAS No.	371-46-0
Molecular Formula	C5H9FO4
Molecular Weight	152.12 g/mol
Synonyms	2,3-Dihydroxypropyl fluoroacetate; Glycerol 1-fluoroacetate; 1-Fluoroacetic acid 2,3-dihydroxypropyl ester; 3-Fluoroacetyl-1,2-propanediol; Fluoroacetic acid monoester with glycerol; Glyceryl monofluoroacetate; 2,3-Dihydroxypropyl 2-fluoroacetate; (2,3-Dihydroxypropoxy)fluoroacetaldehyde (tautomeric form)
EINECS	206-741-6

Quality Control

Every batch of Fluoroacetic Acid 2,3-Dihydroxypropyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting compliance in regulated research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Impurities (HPLC)	Individual ≤ 0.5%, Total ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.