Description

2-(3-Fluorophenyl)Acetamide is a versatile fluorinated aromatic amide building block, essential for advanced organic synthesis and pharmaceutical research. Its core value lies in the strategic incorporation of a fluorine atom, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and pesticides, where the fluorine moiety enhances efficacy and environmental profile.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic processes.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with unique electronic or surface properties.
• Biochemical Probe Synthesis: Utilized in medicinal chemistry to create tool compounds for target validation and mechanism-of-action studies.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up services under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	2-(3-Fluorophenyl)Acetamide
CAS No.	370-45-6
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	3-Fluorophenylacetamide; (3-Fluorophenyl)acetamide; 2-(3-Fluorophenyl)ethanamide; m-Fluorophenylacetamide; 3-Fluorobenzeneacetamide; NSC 403697; 370-45-6; α-Acetamido-3-fluorotoluene
EINECS	206-732-5

Quality Control

Our 2-(3-Fluorophenyl)Acetamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our production can adhere to ISO 9001 standards, and custom synthesis is available under controlled environments suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound is hygroscopic (moisture-sensitive); ensure containers are sealed after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.