Description

Diethyl [(Alpha,Alpha,α-Trifluoro-m-Toluidino)Methylene]Malonate is a high-value fluorinated malonate derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which enables the efficient construction of complex heterocycles and fluorinated target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is utilized to introduce key structural motifs and explore novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including potential anticancer and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that benefit from the stability and lipophilicity imparted by the trifluoromethyl group.
• Material Science Research: Acts as a precursor for novel fluorinated polymers or organic electronic materials with specialized properties.
• Chemical Biology Probes: Employed in the development of tagged or labeled compounds for studying biological mechanisms and interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.
• Academic & Industrial R&D: Fundamental reagent in methodological development for new C-C and C-N bond-forming reactions in organic synthesis.

Basic Information

Product Name	Diethyl [(Alpha,Alpha,α-Trifluoro-m-Toluidino)Methylene]Malonate
CAS No.	370-35-4
Molecular Formula	C15H16F3NO4
Molecular Weight	331.29 g/mol
Synonyms	Diethyl (2-((3-(trifluoromethyl)phenyl)amino)methylene)malonate; Diethyl [(3-(Trifluoromethyl)anilino)methylene]malonate; (α,α,α-Trifluoro-m-toluidino)methylene Malonic Acid Diethyl Ester; Ethyl (E)-2-((3-(trifluoromethyl)phenyl)imino)malonate; Diethyl (N-(3-(trifluoromethyl)phenyl)formimidoyl)malonate; DTMM; NSC 404058
EINECS	206-734-4

Quality Control

Our Diethyl [(Alpha,Alpha,α-Trifluoro-m-Toluidino)Methylene]Malonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.