Description

4-Methylsulfanyl-2-[(2,2,2-Trifluoroacetyl)Amino]Butanoic Acid is a specialized fluorinated amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral building block for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as peptide mimetics and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing fluorinated motifs.
• Peptidomimetics & Bioactive Molecule Synthesis: Used in the construction of modified peptides and peptide-like compounds to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Serves as a building block in the discovery and synthesis of new-generation herbicides, fungicides, and insecticides with improved properties.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	4-Methylsulfanyl-2-[(2,2,2-Trifluoroacetyl)Amino]Butanoic Acid
CAS No.	369-16-4
Molecular Formula	C7H10F3NO3S
Molecular Weight	245.22 g/mol
Synonyms	2-[(2,2,2-Trifluoroacetyl)amino]-4-(methylthio)butanoic acid; 4-(Methylthio)-2-[(trifluoroacetyl)amino]butyric acid; N-(Trifluoroacetyl)-L-methionine; N-Trifluoroacetylmethionine; 4-Methylthio-2-(trifluoroacetamido)butanoic Acid; 2-(Trifluoroacetamido)-4-methylthiobutanoic acid; TFA-Methionine derivative
EINECS	Contact for details

Quality Control

Our 4-Methylsulfanyl-2-[(2,2,2-Trifluoroacetyl)Amino]Butanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.