Description

1-Cyclobutene-1-Carbonitrile,2-Ethoxy-3,3-Difluoro-(9Ci) is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a cyclobutene ring and difluoroethoxy substituent, makes it a valuable precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily utilized by R&D chemists and process development scientists working on novel active ingredients, where its specific reactivity profile enables the introduction of key fluorinated motifs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those requiring fluorinated cyclobutane or cyclobutene scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Research: Serves as a building block in the synthesis of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Precursor: Used in the research and development of specialty polymers and advanced materials that incorporate fluorinated cyclic structures for unique thermal or chemical resistance properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for methodological studies, including cycloaddition reactions and the exploration of new fluorination pathways.

Basic Information

Product Name	1-Cyclobutene-1-Carbonitrile,2-Ethoxy-3,3-Difluoro-(9Ci)
CAS No.	367-41-9
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	2-Ethoxy-3,3-difluoro-1-cyclobutene-1-carbonitrile; 3,3-Difluoro-2-ethoxy-1-cyclobutene-1-carbonitrile; 1-Cyclobutene-1-carbonitrile, 2-ethoxy-3,3-difluoro-; 2-Ethoxy-3,3-difluorocyclobut-1-ene-1-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-Cyclobutene-1-Carbonitrile,2-Ethoxy-3,3-Difluoro-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for critical research applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.