Description

2,4-Dibromo-1,3,5-Trifluorobenzene is a halogenated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its unique reactivity profile, where the strategic placement of bromine and fluorine atoms allows for selective functionalization. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine substituents contribute to biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Cross-Coupling Reactions: The bromine atoms are excellent leaving groups for palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira), enabling the construction of complex biaryl structures.
• Fluorine Chemistry Studies: An important reagent for investigating nucleophilic aromatic substitution (SNAr) reactions specific to fluorinated arenes.

Basic Information

Product Name	2,4-Dibromo-1,3,5-Trifluorobenzene
CAS No.	363-69-9
Molecular Formula	C6HBr2F3
Molecular Weight	291.87 g/mol
Synonyms	1,3,5-Trifluoro-2,4-dibromobenzene; Benzene, 2,4-dibromo-1,3,5-trifluoro-; 2,4-Dibromo-1,3,5-trifluorobenzol; NSC 169062; AI3-52733; DBTFB; 2,4-Dibrom-1,3,5-trifluorbenzol (German); 2,4-ジブロモ-1,3,5-トリフルオロベンゼン (Japanese)
EINECS	Contact for details

Quality Control

Our production of 2,4-Dibromo-1,3,5-Trifluorobenzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.