Description

Stearoyl Coenzyme A is a critical long-chain fatty acyl-CoA ester that serves as a key metabolic intermediate in lipid biosynthesis and degradation pathways. Its primary value lies in its role as a high-specificity substrate for enzymatic research, particularly in studies of fatty acid metabolism, desaturation, and elongation. This compound is essential for biochemical and pharmaceutical research laboratories, biotechnology companies, and academic institutions focused on lipid biology, metabolic disease research, and enzyme kinetics.

Application

• Enzymology Research: As a specific substrate for studying Stearoyl-CoA Desaturase (SCD1) activity, a key enzyme in monounsaturated fatty acid synthesis.
• Metabolic Pathway Analysis: Investigating β-oxidation and fatty acid elongation cycles within cellular mitochondria and peroxisomes.
• Lipidomics & Biochemical Assay Development: Used in the development and validation of high-throughput assays to measure lipid metabolism and enzyme function.
• Pharmaceutical Screening: Serving as a target molecule for drug discovery programs aimed at metabolic disorders, such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD).
• Cell Biology Studies: Exploring the role of lipid intermediates in cellular signaling, membrane biogenesis, and energy homeostasis.
• Reference Standard: Employed as a pure analytical standard in LC-MS, HPLC, and other chromatographic methods for lipid identification and quantification.

Basic Information

Product Name	Stearoyl Coenzyme A
CAS No.	362-66-3
Molecular Formula	C₃₉H₇₂N₇O₁₇P₃S
Molecular Weight	1000.00 g/mol (approx.)
Synonyms	Stearoyl-CoA; Octadecanoyl-CoA; Coenzyme A, S-octadecanoyl; Octadecanoyl-coenzyme A; Stearic Acid Coenzyme A Ester; C18:0-CoA; S-Stearoylcoenzyme A; Stearoyl-Coenzyme A Lithium Salt (common form)
EINECS	Contact for details

Quality Control

Our Stearoyl Coenzyme A is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous analytical standards, with quality assurance practices designed to meet the needs of pharmaceutical and advanced biochemical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Conforms (Enzymatic Assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.