Description

n-Methylchlorpromazine is a key pharmaceutical intermediate and research chemical, primarily known for its role in the synthesis of phenothiazine-derived compounds. Its importance lies in providing a versatile building block for medicinal chemistry research and the development of active pharmaceutical ingredients (APIs). This compound is essential for R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on neuropharmacology and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chlorpromazine analogs and other phenothiazine-based therapeutic agents.
• Medicinal Chemistry Research: Used as a standard or building block in structure-activity relationship (SAR) studies for central nervous system (CNS) drug candidates.
• Biochemical Research: Employed in studies investigating dopamine receptor interactions and the pharmacological mechanisms of antipsychotic drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Utilized in university and corporate research settings for the discovery and optimization of new chemical entities.

Basic Information

Product Name	n-Methylchlorpromazine
CAS No.	362-02-7
Molecular Formula	C18H21ClN2S
Molecular Weight	332.89 g/mol
Synonyms	N-Methylchlorpromazine; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine; Chlorpromazine N-Methyl Derivative; 10-[3-(Dimethylamino)propyl]-2-chlorophenothiazine; 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine; N-Methyl-2-chloro-10-(3-dimethylaminopropyl)phenothiazine; Levomepromazine Impurity
EINECS	Contact for details

Quality Control

Our n-Methylchlorpromazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.