Description

Bis(4-Fluorophenyl)Acetic Acid CAS NO 361-63-7 is a high-purity fluorinated aromatic compound serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates two para-fluorophenyl groups, making it an essential precursor for pharmaceuticals and specialty materials. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and liquid crystal industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its influence on molecular polarity and alignment.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and host materials in OLED device fabrication.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination chemistry and creating complex molecular architectures.

Basic Information

Product Name	Bis(4-Fluorophenyl)Acetic Acid
CAS No.	361-63-7
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	2,2-Bis(4-fluorophenyl)acetic acid; Di(p-fluorophenyl)acetic acid; α,α-Bis(4-fluorophenyl)acetic acid; 4,4'-Difluorodiphenylacetic acid; (4,4'-Difluorodiphenyl)acetic acid; NSC 163082; BIS(4-FLUOROPHENYL)ACETIC ACID; p,p'-Difluorodiphenylacetic acid
EINECS	Contact for details

Quality Control

Our Bis(4-Fluorophenyl)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.