Description

N,n-Diethyl-2,2,2-Trifluoroacetamide is a versatile fluorinated acetamide derivative characterized by its trifluoromethyl group, which imparts unique chemical and physical properties. This compound is a critical intermediate and reagent in advanced organic synthesis, particularly valued for introducing fluorine-containing moieties into target molecules. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where its structural features are leveraged to enhance product performance and stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoroacetamide or related fluorinated structures for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to enhanced efficacy and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile reagent for amidation and fluorination reactions, facilitating the construction of complex molecules in research and development laboratories.
• Liquid Crystal & Electronic Materials: Acts as a precursor or additive in the manufacturing of fluorinated liquid crystals and specialty polymers for electronic applications.
• Chemical Research: Employed in academic and industrial R&D for studying reaction mechanisms and developing new synthetic methodologies involving fluoroorganic compounds.

Basic Information

Product Name	N,n-Diethyl-2,2,2-Trifluoroacetamide
CAS No.	360-92-9
Molecular Formula	C6H10F3NO
Molecular Weight	169.15 g/mol
Synonyms	2,2,2-Trifluoro-N,N-diethylacetamide; Diethyltrifluoroacetamide; N,N-Diethyl-2,2,2-trifluoroacetamide; Trifluoroacetic Acid Diethylamide; TFA Diethylamide; Acetamide, 2,2,2-trifluoro-N,N-diethyl-; NSC 92440
EINECS	206-637-6

Quality Control

Our N,n-Diethyl-2,2,2-Trifluoroacetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the highest standards of purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures reliability for your most demanding synthesis and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.390 - 1.400
Density (20°C)	1.15 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.