Description

2-Chloro-3,3,4,4-Tetrafluoro-1-Cyclobuten-1-Yl(Ethyl) Ether is a specialized fluorinated cyclobutene derivative, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring a reactive chloro and ether group on a perfluorinated cyclobutene ring, makes it a critical precursor for synthesizing complex fluorinated molecules. This compound is essential for R&D and production in the pharmaceutical and agrochemical industries, where the introduction of fluorine atoms is a key strategy for modulating the biological activity, metabolic stability, and physical properties of target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where fluorination enhances efficacy and environmental profile.
• Fluorinated Material Precursor: Serves as a monomer or intermediate for creating specialty polymers, liquid crystals, and electronic materials with unique thermal, chemical, and surface properties.
• Organic Synthesis Reagent: Employed in research laboratories for constructing complex, fluorinated heterocycles and other architecturally challenging molecules via cycloaddition or substitution reactions.
• Fine Chemical Production: Integral to the synthesis of high-value fluorinated fine chemicals and dyes used in various industrial applications.

Basic Information

Product Name	2-Chloro-3,3,4,4-Tetrafluoro-1-Cyclobuten-1-Yl(Ethyl) Ether
CAS No.	360-13-4
Molecular Formula	C6H5ClF4O
Molecular Weight	204.55 g/mol
Synonyms	Ethyl 2-Chloro-3,3,4,4-tetrafluorocyclobut-1-ene-1-carboxylate; 2-Chloro-3,3,4,4-tetrafluorocyclobut-1-en-1-yl ethyl ether; 1-Chloro-2-ethoxy-3,3,4,4-tetrafluorocyclobut-1-ene; (2-Chloro-3,3,4,4-tetrafluorocyclobutenyl) ethyl ether; 360-13-4; Ethyl 2-chloroperfluorocyclobut-1-ene-1-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,3,4,4-Tetrafluoro-1-Cyclobuten-1-Yl(Ethyl) Ether is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high purity and consistent composition suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.