Description

1,1,1,3-Tetrafluoroacetone is a highly fluorinated ketone derivative, valued for its unique reactivity as a versatile building block in advanced chemical synthesis. Its molecular structure, featuring a trifluoromethyl group and a difluoromethyl group, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby enhancing their properties. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty materials sectors, where fluorinated compounds are increasingly important.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides with improved efficacy and environmental profiles.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the development of specialty polymers, coatings, and surfactants with enhanced chemical resistance and stability.
• Organic Synthesis & R&D: A versatile reagent for introducing the CF3-CF2- moiety in complex organic molecules for research and fine chemical production.
• Electrolyte Additive: Investigated for use in advanced lithium-ion battery electrolytes to improve performance and safety.
• Refrigerant & Propellant Research: Potential application in next-generation, low-global-warming-potential (GWP) fluorocarbon blends.

Basic Information

Product Name	1,1,1,3-Tetrafluoroacetone
CAS No.	359-43-3
Molecular Formula	C3H2F4O
Molecular Weight	130.04 g/mol
Synonyms	1,1,1,3-Tetrafluoro-2-propanone; 1,1,1,3-Tetrafluoroacetone; Perfluoro-tert-butyl alcohol precursor; TFAP; 3,3,3-Trifluoro-1,1-difluoroacetone; 1,1,1-Trifluoro-3,3-difluoroacetone; Hexafluoroacetone isomer; F-Acetone derivative
EINECS	Contact for details

Quality Control

Our 1,1,1,3-Tetrafluoroacetone is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets precise specifications for purity and identity. Certificates of Analysis (COA) detailing key parameters are provided and available upon request, supporting compliance in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids, bases, and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed to prevent evaporation and moisture ingress. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.45 g/mL
Boiling Point	~40-45°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.