Description

Propionic Acid, 2,2,3,3-Tetrafluoro-3-(Trifluoromethoxy)-, Methyl Ester is a highly fluorinated methyl ester derivative of propionic acid, characterized by its unique perfluoroalkoxy substituent. This compound matters for its exceptional chemical and thermal stability, making it a valuable intermediate for synthesizing advanced materials. It is primarily needed by manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for the development of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, fungicides, and insecticides with improved efficacy and environmental profile.
• Fluorinated Polymer Production: Acts as a monomer or modifier in the production of specialty polymers, imparting properties like oil repellency, chemical resistance, and low surface energy.
• Liquid Crystal & Electronic Materials: Employed in the development of fluorinated liquid crystals and dielectric fluids for advanced electronic and display applications.
• Surface Modification Agent: Used to create hydrophobic and oleophobic coatings for textiles, membranes, and electronic components.
• Organic Synthesis Reagent: A versatile fluorinated synthon in research and development for introducing the 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)propionyl moiety into target molecules.

Basic Information

Product Name	Propionic Acid, 2,2,3,3-Tetrafluoro-3-(Trifluoromethoxy)-, Methyl Ester
CAS No.	356-69-4
Molecular Formula	C5H3F7O3
Molecular Weight	244.07 g/mol
Synonyms	Methyl 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)propionate; Methyl perfluoro(3-methoxypropionate); 3-(Trifluoromethoxy)-2,2,3,3-tetrafluoropropionic Acid Methyl Ester; 2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propionic Acid Methyl Ester; Propanoic acid, 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)-, methyl ester; Methyl 3-(trifluoromethoxy)-2,2,3,3-tetrafluoropropanoate
EINECS	Contact for details

Quality Control

Our Propionic Acid, 2,2,3,3-Tetrafluoro-3-(Trifluoromethoxy)-, Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids/organic solvents and fluorides/strong alkalis. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.55 g/mL
Refractive Index (n20/D)	~1.315

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.