Description

Methyl 2,2,3,3,4,4-hexafluorobutanoate is a high-purity fluorinated ester building block, valued for its unique combination of fluorine's electronic and steric properties within an ester functionality. This compound is essential for introducing lipophilicity and metabolic stability into target molecules during advanced chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for introducing fluorinated moieties into drug candidates to enhance bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where fluorine atoms improve efficacy and environmental persistence.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier for creating specialty polymers with enhanced chemical resistance, low surface energy, and unique optical properties.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for display technologies and dielectric fluids.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and as a precursor to other fluorinated acids and alcohols in research laboratories.
• Surface Treatment & Coatings: Acts as a starting material for fluorinated surfactants and coating additives that provide oil, water, and stain repellency.

Basic Information

Product Name	Methyl 2,2,3,3,4,4-Hexafluorobutanoate
CAS No.	356-32-1
Molecular Formula	C5H4F6O2
Molecular Weight	210.08 g/mol
Synonyms	Methyl Perfluorobutyrate; Methyl 4,4,4-Trifluoro-3-(trifluoromethyl)butanoate; 2,2,3,3,4,4-Hexafluorobutanoic Acid Methyl Ester; Methyl Hexafluorobutyrate; Methyl 2,2,3,3,4,4-Hexafluorobutyrate; Perfluorobutyric Acid Methyl Ester; MFB; Methyl Perfluorobutanoate
EINECS	Contact for details

Quality Control

Our Methyl 2,2,3,3,4,4-hexafluorobutanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high chemical purity and lot-to-lot consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container should be kept tightly sealed to minimize moisture uptake and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 1.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.