Description

3-(4-Fluoro-Phenyl)-Acrylic Acid Ethyl Ester is a versatile fluorinated acrylate ester building block, prized for its role in synthesizing complex organic molecules. Its core value lies in the reactivity of the acrylate double bond and the electronic influence of the para-fluoro substituent, enabling precise structural modifications. This compound is essential for R&D chemists and process developers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce fluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated styryl or cinnamic acid derivative scaffold.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Polymer & Resin Modifier: Incorporated as a co-monomer to impart specific properties like UV stability, chemical resistance, or altered refractive index to specialty polymers.
• Organic Synthesis & Research: Employed in Heck reactions, Michael additions, and other coupling reactions to construct complex molecules for chemical research.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of fluorinated aromatic compounds for specialty fragrance applications.

Basic Information

Item	Detail
Product Name	3-(4-Fluoro-Phenyl)-Acrylic Acid Ethyl Ester
CAS No.	352-03-4
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	Ethyl 3-(4-Fluorophenyl)acrylate; Ethyl 4-Fluorocinnamate; (E)-Ethyl 3-(4-fluorophenyl)acrylate; 4-Fluorocinnamic Acid Ethyl Ester; trans-Ethyl 4-fluorocinnamate; Ethyl (E)-3-(4-fluorophenyl)-2-propenoate; 3-(p-Fluorophenyl)acrylic Acid Ethyl Ester; NSC 404083
EINECS	206-517-7

Quality Control

Our 3-(4-Fluoro-Phenyl)-Acrylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Typical 99.0%)
Isomeric Purity (GC/HPLC)	≥ 99.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.