Description

4-Trifluoromethylaceto-Acetanilide is a specialized fluorinated organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its trifluoromethyl group, which imparts unique electronic and steric properties, enhancing the biological activity and metabolic stability of target molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylated aniline moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Dye and Pigment Manufacturing: Serves as a precursor for specialty dyes and functional pigments, leveraging its aromatic amine structure.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals with tailored optical and electronic properties.
• Organic Synthesis Reagent: Acts as a versatile reagent in academic and industrial research for introducing the acetoacetanilide functional group into complex molecules.

Basic Information

Product Name	4-Trifluoromethylaceto-Acetanilide
CAS No.	351-87-1
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	N-(4-Trifluoromethylphenyl)-3-oxobutanamide; 4'-(Trifluoromethyl)acetoacetanilide; 1-(4-Trifluoromethylphenylamino)-1,3-butanedione; Acetoacet-4-trifluoromethylanilide; TFAA; 4-Trifluoromethyl Aceto Acetanilide; α-Acetyl-4'-(trifluoromethyl)acetanilide; N-(4-Trifluoromethylphenyl)acetoacetamide
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethylaceto-Acetanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.