Description

Benzyl Trifluoromethyl Sulfide is a versatile organosulfur compound featuring a benzyl group linked to a trifluoromethylthio moiety. This structure makes it a valuable synthetic intermediate and building block in advanced chemical synthesis, particularly for introducing the highly lipophilic and electron-withdrawing SCF3 group. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams seeking to modulate the biological activity and physical properties of novel molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing the trifluoromethylthioether group, which can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the SCF3 group can contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or modifying agent in the development of specialty polymers and functional materials with unique surface or electronic properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of novel ligands and catalysts used in cross-coupling and other catalytic reactions.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on incorporating fluorine and sulfur functionalities into organic frameworks.
• Fine Chemical Production: Acts as a versatile synthon in the multistep synthesis of complex fine chemicals and specialty flavors or fragrances.

Basic Information

Product Name	Benzyl Trifluoromethyl Sulfide
CAS No.	351-60-0
Molecular Formula	C8H7F3S
Molecular Weight	192.20 g/mol
Synonyms	(Trifluoromethylthio)methylbenzene; α-(Trifluoromethylthio)toluene; Benzyl Trifluoromethyl Thioether; S-(Trifluoromethyl)benzyl Mercaptan; Phenylmethyl Trifluoromethyl Sulfide; Benzylthio Trifluoromethane; 1-(Trifluoromethylthio)methylbenzene; Toluene, α-(trifluoromethylthio)-
EINECS	Contact for details

Quality Control

Our Benzyl Trifluoromethyl Sulfide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.480 - 1.490
Density	1.28 - 1.32 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.