Description

(1,1,2,2-Tetrafluoroethoxy)Benzene is a specialized fluorinated aromatic ether compound. This high-value intermediate is prized for its unique combination of an aromatic ring and a perfluorinated ethoxy side chain, offering distinct chemical and physical properties. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel compounds with enhanced stability and performance.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability, bioavailability, and lipophilicity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the introduction of fluorine atoms can significantly enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), contributing to improved dielectric anisotropy, thermal stability, and optical properties.
• Specialty Polymer Modifier: Incorporated into polymer chains to impart specific characteristics such as chemical resistance, low surface energy, and altered solubility profiles for high-performance coatings and resins.
• Organic Synthesis Reagent: Employed in research laboratories as a versatile reagent for introducing the tetrafluoroethoxy functional group into complex molecular architectures via etherification or cross-coupling reactions.

Basic Information

Product Name	(1,1,2,2-Tetrafluoroethoxy)Benzene
CAS No.	350-57-2
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	Benzene, (1,1,2,2-tetrafluoroethoxy)-; 1,1,2,2-Tetrafluoroethoxybenzene; α,α,β,β-Tetrafluoroethoxybenzene; 2,2,3,3-Tetrafluoroethyl Phenyl Ether; Phenyl 2,2,3,3-tetrafluoroethyl ether; (Perfluoroethoxy)benzene; Tetrafluoroethoxyphenyl
EINECS	Contact for details

Quality Control

Every batch of (1,1,2,2-Tetrafluoroethoxy)Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA), including results from GC, HPLC, NMR, and other relevant analytical techniques, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, strong bases, and oxidizing agents. For long-term storage, maintaining the container under an inert atmosphere (e.g., nitrogen or argon) is recommended to preserve product integrity. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Assay (GC / HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances / Impurities (GC)	≤ 1.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.