Description

2-(4-(Trifluoromethyl)Phenylthio)Acetic Acid is a specialized organosulfur compound featuring a trifluoromethylphenylthio moiety attached to an acetic acid backbone. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for introducing sulfur and fluorine-containing groups. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams seeking to create novel molecules with modified properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring bioisosteric replacement or metabolic stability enhancement.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl and thioether groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the research and production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for constructing complex sulfur- and fluorine-containing heterocycles and other novel organic frameworks in academic and industrial labs.

Basic Information

Product Name	2-(4-(Trifluoromethyl)Phenylthio)Acetic Acid
CAS No.	349-83-7
Molecular Formula	C9H7F3O2S
Molecular Weight	236.21 g/mol
Synonyms	2-[[4-(Trifluoromethyl)phenyl]thio]acetic Acid; α-[(4-Trifluoromethylphenyl)thio]acetic Acid; 4-(Trifluoromethyl)thiophenoxyacetic Acid; (4-Trifluoromethylphenylthio)acetic Acid; Acetic Acid, 2-[(4-(trifluoromethyl)phenyl)thio]-; TFPAA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-(4-(Trifluoromethyl)Phenylthio)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.