Description

2-(Trifluoromethyl)Benzoic Acid Hydrazide is a versatile trifluoromethylated aromatic hydrazide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the hydrazide functional group and the electron-withdrawing properties imparted by the trifluoromethyl substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of heterocyclic compounds, including pyrazoles, triazoles, and other nitrogen-containing bioactive molecules with potential therapeutic applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the production of high-performance polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating libraries of fluorinated compounds.
• Material Science: Used in the synthesis of organic electronic materials, liquid crystals, and other advanced functional materials where fluorine substitution is beneficial.

Basic Information

Product Name	2-(Trifluoromethyl)Benzoic Acid Hydrazide
CAS No.	344-95-6
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	2-(Trifluoromethyl)benzohydrazide; α,α,α-Trifluoro-o-toluic acid hydrazide; o-(Trifluoromethyl)benzhydrazide; 2-Trifluoromethylbenzhydrazide; Benzoic acid, 2-(trifluoromethyl)-, hydrazide; 2-Trifluoromethylbenzoyl hydrazine; (2-Trifluoromethylphenyl)carbamoyl hydrazine
EINECS	206-469-5

Quality Control

Our 2-(Trifluoromethyl)Benzoic Acid Hydrazide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For customers with specific regulatory needs, we can support documentation for cGMP, ISO, or other quality standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening containers for use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.