Description

3,5-Difluoro-4-Methoxybenzamide is a high-purity fluorinated benzamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates fluorine and methoxy substituents to modulate the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro-methoxy motif enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED device fabrication.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing novel fluorination methodologies.
• Custom Synthesis: A versatile starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	3,5-Difluoro-4-Methoxybenzamide
CAS No.	343-79-3
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	4-Methoxy-3,5-difluorobenzamide; 3,5-Difluoro-4-methoxybenzoic acid amide; 3,5-Difluoro-p-anisamide; Benzamide, 3,5-difluoro-4-methoxy-; 343-79-3; 4-Methoxy-3,5-difluorobenzoic acid amide
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Methoxybenzamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.