Description

3-Acetylpyridine-Adenine Dinucleotide Phosphate is a chemically modified analog of the essential coenzyme NADP+. This compound serves as a critical biochemical tool, enabling researchers to probe and manipulate specific enzymatic pathways with high selectivity. It is primarily utilized in life science research, pharmaceutical development, and diagnostic applications where precise control over redox reactions is required.

Application

• Enzymology Research: As a substrate analog for studying the mechanism and kinetics of NADP+-dependent dehydrogenases and reductases.
• Pharmaceutical Screening: Used in high-throughput assays to identify and characterize potential inhibitors or activators of specific metabolic enzymes.
• Metabolic Pathway Analysis: A tool for investigating cellular redox states and metabolic flux in pathways such as the pentose phosphate pathway.
• Diagnostic Reagent Development: A key component in the formulation of diagnostic kits for clinical chemistry, measuring specific enzyme activities.
• Biocatalysis: Employed in enzymatic synthesis processes that require a modified cofactor to drive novel or non-natural reactions.
• Cell Biology Studies: Used to modulate intracellular NADP+ levels and study the effects on cell signaling, oxidative stress, and apoptosis.

Basic Information

Product Name	3-Acetylpyridine-Adenine Dinucleotide Phosphate
CAS No.	341-67-3
Molecular Formula	C22H28N7O17P3
Molecular Weight	779.40 g/mol
Synonyms	3-Acetylpyridine NADP; 3-Acetylpyridine Adenine Dinucleotide Phosphate; Acetylpyridine NADP; 3-APADP; 3-Acetylpyridine-NADP; 3-Pyridineacetamide, N-(aminocarbonyl)-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, inner salt, 5'-ester with adenosine 5'-(trihydrogen diphosphate); 3-AcPy-ADP
EINECS	Contact for details

Quality Control

Our 3-Acetylpyridine-Adenine Dinucleotide Phosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity verification, to ensure it meets the stringent requirements of research and diagnostic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.