Description

(4,4-Dichloro-3,3-Difluoro-1-Cyclobutenyl)Benzene is a specialized fluorinated and chlorinated cyclobutene derivative, serving as a high-value synthetic intermediate. Its unique structure, featuring a strained cyclobutene ring with halogen substituents, makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by material scientists exploring new polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated or strained ring systems for enhanced bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the difluorocyclobutene moiety can impart unique properties.
• Advanced Material Research: Serves as a monomer or building block for specialty polymers, liquid crystals, and organic electronic materials due to its rigid, halogenated structure.
• Organic Synthesis & Catalysis: Employed in academic and industrial research as a versatile substrate for exploring new halogenation, cycloaddition, and cross-coupling reactions.
• Fluorine Chemistry: An important reagent for introducing both fluorine and chlorine atoms into complex molecular architectures in a single step.

Basic Information

Item	Details
Product Name	(4,4-Dichloro-3,3-Difluoro-1-Cyclobutenyl)Benzene
CAS No.	340-01-2
Molecular Formula	C10H6Cl2F2
Molecular Weight	235.06 g/mol
Synonyms	1,2-Dichloro-3,3-difluoro-4-phenylcyclobut-1-ene; 4,4-Dichloro-3,3-difluoro-1-phenyl-1-cyclobutene; 1-Phenyl-4,4-dichloro-3,3-difluorocyclobut-1-ene; (4,4-Dichloro-3,3-difluorocyclobut-1-en-1-yl)benzene; Benzene, (4,4-dichloro-3,3-difluoro-1-cyclobuten-1-yl)-; 340-01-2; NSC 163082
EINECS	Contact for details

Quality Control

Every batch of (4,4-Dichloro-3,3-Difluoro-1-Cyclobutenyl)Benzene is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride ions; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.