Description

Methyl 2-Fluoro-2-Methylpropionate is a versatile fluorinated ester building block of significant interest in advanced organic synthesis. Its value lies in the introduction of a fluorine atom and a sterically hindered ester group, enabling precise modification of molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom to improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a fluorinated monomer for creating high-performance electronic and display materials with tailored dielectric and optical properties.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing characteristics like chemical resistance, surface energy, and thermal stability.
• Organic Synthesis Reagent: Acts as a fluorinated electrophile or a protected carboxylic acid equivalent in complex multi-step synthetic routes.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of novel, complex aroma chemicals where the fluorine atom can subtly alter scent profiles and stability.

Basic Information

Product Name	Methyl 2-Fluoro-2-Methylpropionate
CAS No.	338-76-1
Molecular Formula	C5H9FO2
Molecular Weight	120.12 g/mol
Synonyms	2-Fluoro-2-methylpropionic acid methyl ester; Methyl α-fluoroisobutyrate; Methyl 2-fluoroisobutyrate; Methyl 2-fluoro-2-methylpropanoate; α-Fluoroisobutyric acid methyl ester; 2-Fluoro-2-methylpropanoic acid methyl ester; Isobutyric acid, 2-fluoro-, methyl ester; MFP
EINECS	206-409-9

Quality Control

Our Methyl 2-Fluoro-2-Methylpropionate is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) specifying identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain product integrity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Refractive Index (20°C)	1.380 - 1.390
Density (20°C)	1.02 - 1.06 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.