Description

Cyclobutanecarboxylic Acid, 1-Fluoro-, Ethyl Ester (6Ci,8Ci,9Ci) is a specialized fluorinated cyclobutane derivative, a high-value building block in advanced organic synthesis. Its unique strained-ring structure combined with a fluorine atom and an ester group makes it a critical intermediate for developing novel compounds with targeted properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate fluorinated cyclobutane motifs into their molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing the metabolically stable fluorocyclobutyl group.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorinated cyclobutane structure can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, influencing dielectric anisotropy and improving device performance.
• Polymer Modification: Employed to introduce fluorinated cyclobutane units into polymer backbones, potentially altering thermal stability, chemical resistance, and surface properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways, catalysis, and the synthesis of complex fluorinated architectures.
• Fluorine Chemistry Library Building: Used for constructing diverse screening libraries in drug discovery and materials science to explore structure-activity relationships (SAR).

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1-Fluoro-, Ethyl Ester (6Ci,8Ci,9Ci)
CAS No.	337-98-4
Molecular Formula	C7H11FO2
Molecular Weight	146.16 g/mol
Synonyms	Ethyl 1-Fluorocyclobutanecarboxylate; 1-Fluorocyclobutanecarboxylic Acid Ethyl Ester; 1-Fluoro-cyclobutanecarboxylic acid ethyl ester; Ethyl 1-fluorocyclobutan-1-carboxylate; 1-Fluorocyclobutane-1-carboxylic Acid Ethyl Ester; NSC 3341; F-Cyclobutane-COOEt
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 1-Fluoro-, Ethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis or specific grade requirements (e.g., research grade, >98% purity), our technical team can tailor the quality control parameters to meet your project's exact needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95%
Water Content (KF)	≤ 0.5%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.