Description

2,2,3,3-Tetrafluoropropanoic Anhydride, also known as 2,2,3,3-Tetrafluoropropionic Anhydride, is a highly reactive fluorinated acid anhydride derivative. This compound is a critical reagent for introducing the tetrafluoropropionyl group, valued for its strong electron-withdrawing properties and ability to modify chemical stability and lipophilicity. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), where the fluorine atoms can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging fluorine's ability to improve weatherfastness and biological activity.
• Polymer & Material Science: Serves as a monomer or modifier in the creation of specialty fluoropolymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic displays and organic light-emitting diodes to optimize performance and longevity.
• Derivatization Agent for Analysis: Acts as a derivatizing agent in gas chromatography and mass spectrometry for analyzing compounds containing active hydrogens.
• Organic Synthesis Reagent: Facilitates acylation reactions in complex organic synthesis, particularly where a robust, fluorinated protecting or activating group is needed.

Basic Information

Product Name	2,2,3,3-Tetrafluoropropanoic Anhydride / 2,2,3,3-Tetrafluoropropionic Anhydride
CAS No.	337-83-7
Molecular Formula	C6H2F8O3
Molecular Weight	274.07 g/mol
Synonyms	Perfluoropropionic Anhydride; Tetrafluoropropionic Anhydride; 2,2,3,3-Tetrafluoropropanoic Acid Anhydride; 2,2,3,3-Tetrafluoropropionyl Anhydride; PFP Anhydride; Propanoic Acid, 2,2,3,3-Tetrafluoro-, Anhydride; Bis(2,2,3,3-tetrafluoropropanoyl) Ether; 2,2,3,3-Tetrafluoropropionic Acid Anhydride
EINECS	Contact for details

Quality Control

Our 2,2,3,3-Tetrafluoropropionic Anhydride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including assay by GC or HPLC and impurity profiling, to ensure it meets the high-purity standards required for sensitive applications like pharmaceutical R&D and electronic materials. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific impurity limits is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong bases, amines, and alcohols. Due to its nature as a strong acid/organic solvent, containers must be kept tightly sealed to prevent moisture absorption and hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 1.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.