Description

Ethyl 2,2,3,3-tetrafluoropropionate is a versatile fluorinated ester building block, valued for its unique chemical reactivity and properties. This compound is essential for introducing the tetrafluoropropionate moiety into target molecules, enabling the synthesis of advanced materials and fine chemicals. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in fluorination chemistry and as a key intermediate.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring fluorinated components for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor for developing advanced pesticides and herbicides, where fluorine atoms can improve efficacy and environmental profile.
• Fluorinated Polymer & Material Science: Acts as a monomer or modifier in the production of specialty polymers, coatings, and materials with enhanced chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in various organic transformations, including esterifications, cross-coupling reactions, and nucleophilic substitutions, to construct complex fluorinated molecules.
• Liquid Crystal & Electronic Chemicals: Utilized in the development of fluorinated components for liquid crystal displays (LCDs) and other electronic materials.
• Solvent & Reaction Medium: Functions as a specialty fluorinated solvent for specific chemical processes requiring unique solvation properties.

Basic Information

Product Name	Ethyl 2,2,3,3-Tetrafluoropropionate
CAS No.	337-82-6
Molecular Formula	C5H6F4O2
Molecular Weight	174.10 g/mol
Synonyms	2,2,3,3-Tetrafluoropropionic Acid Ethyl Ester; Ethyl Tetrafluoropropionate; Ethyl Perfluoropropionate; Ethyl 2,2,3,3-Tetrafluoropropanoate; NSC 9235; Tetrafluoropropionic Acid Ethyl Ester; Propanoic acid, 2,2,3,3-tetrafluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2,2,3,3-tetrafluoropropionate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.335 - 1.345
Density (20°C)	1.30 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.