Description

Pentafluoropropionaldehyde Ethyl Hemiacetal is a versatile fluorinated building block essential for advanced organic synthesis. Its value lies in providing a protected, stable form of pentafluoropropionaldehyde, enabling precise introduction of the perfluoropropyl group into target molecules. This compound is particularly needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging the unique properties of fluorine to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the perfluoropropyl moiety enhances lipophilicity and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric materials, improving performance and thermal stability.
• Polymer & Surface Modification: Employed to introduce fluorine into polymer backbones or surfaces, imparting valuable properties like oil/water repellency, chemical resistance, and low surface energy.
• Organic Synthesis & Catalysis: Acts as a specialized reagent in nucleophilic addition and cross-coupling reactions to construct complex fluorinated architectures.

Basic Information

Product Name	Pentafluoropropionaldehyde Ethyl Hemiacetal
CAS No.	337-28-0
Molecular Formula	C5H7F5O2
Molecular Weight	194.10 g/mol
Synonyms	1-Ethoxy-2,2,3,3,3-pentafluoropropanol; 2,2,3,3,3-Pentafluoropropionaldehyde ethyl hemiacetal; Ethyl 2,2,3,3,3-pentafluoro-1-hydroxypropyl ether; Pentafluoropropanal ethyl hemiacetal; 1,1-Diethoxy-2,2,3,3,3-pentafluoropropane (related acetal); PFP ethyl hemiacetal
EINECS	Contact for details

Quality Control

Our Pentafluoropropionaldehyde Ethyl Hemiacetal is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area. Due to its highly volatile nature, keep containers tightly sealed when not in use and away from heat sources and open flames. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.