Description

Propanoic Acid, 3,3,3-Trifluoro-2-Hydroxy-2-Methyl-, Methyl Ester is a specialized fluorinated organic ester with a unique trifluoromethyl and hydroxyl group structure. This compound is a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, valued for its ability to introduce fluorine atoms to enhance metabolic stability and bioavailability. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl group for improved drug efficacy and pharmacokinetics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine moiety contributes to enhanced biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Specialty Polymer Modifier: Employed to introduce fluorine into polymer chains, improving properties like chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D for constructing complex organic molecules, leveraging its reactive ester and hydroxyl groups.

Basic Information

Product Name	Propanoic Acid, 3,3,3-Trifluoro-2-Hydroxy-2-Methyl-, Methyl Ester
CAS No.	337-16-6
Molecular Formula	C6H7F3O3
Molecular Weight	184.11 g/mol
Synonyms	Methyl 3,3,3-Trifluoro-2-hydroxy-2-methylpropionate; 2-Hydroxy-2-methyl-3,3,3-trifluoropropionic Acid Methyl Ester; 3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid Methyl Ester; Trifluorolactic Acid Methyl Ester, 2-Methyl Derivative; α-Hydroxy-α-methyl-β,β,β-trifluoropropionic Acid Methyl Ester; TFHMP Methyl Ester; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3,3,3-Trifluoro-2-Hydroxy-2-Methyl-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.