Description

Trifluoro-Nitro-Methane is a versatile fluorinated nitroalkane building block of significant interest in advanced chemical synthesis. Its unique structure, combining a strong electron-withdrawing nitro group with a highly fluorinated methyl group, makes it a valuable precursor for introducing the trifluoromethylnitromethyl moiety into target molecules. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical sectors. It serves as a key intermediate for the synthesis of complex molecules, including potential active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for synthesizing novel drug candidates, particularly those requiring fluorinated scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Organic Synthesis Reagent: Acts as a versatile reagent in nucleophilic substitution and addition reactions, enabling the construction of complex nitro- and fluorine-containing compounds.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and energetic materials with unique properties.
• Fluorine Chemistry Studies: Employed in academic and industrial R&D to study the reactivity and applications of polyfluorinated nitroalkanes.

Basic Information

Product Name	Trifluoro-Nitro-Methane
CAS No.	335-02-4
Molecular Formula	CF3NO2
Molecular Weight	115.02 g/mol
Synonyms	Nitrotrifluoromethane; Trifluoronitromethane; Perfluoronitromethane; Fluorocarbon Nitro; TFNM; FC-13NO2; 1,1,1-Trifluoronitromethane
EINECS	206-387-0

Quality Control

Our Trifluoro-Nitro-Methane is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP requirements for pharmaceutical intermediates, and we comply with relevant global regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases, reducing agents, and metals. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended long-term storage temperature is between 2°C and 8°C (refrigerated) to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.50 - 1.55 g/mL
Boiling Point	Approx. -15°C to -10°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.