Description

(4-Fluorophenylthio)Acetic Acid is a versatile organosulfur building block characterized by a thioether-linked acetic acid moiety attached to a fluorinated aromatic ring. This molecular architecture makes it a valuable intermediate for synthesizing more complex molecules in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications requiring the introduction of a fluorinated phenylthioacetic acid functional group.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom and thioether linkage can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Polymer Modification: Employed to introduce specific functional groups into polymer chains, altering properties like adhesion, solubility, or reactivity for advanced material applications.
• Bioconjugation and Probe Synthesis: Useful in life sciences for creating fluorescent probes, affinity labels, or other bioconjugation reagents due to its reactive carboxylic acid group.
• Organic Synthesis Building Block: A fundamental starting material for constructing more complex heterocyclic compounds and fine chemicals in research laboratories.

Basic Information

Product Name	(4-Fluorophenylthio)Acetic Acid
CAS No.	332-51-4
Molecular Formula	C8H7FO2S
Molecular Weight	186.20 g/mol
Synonyms	2-[(4-Fluorophenyl)sulfanyl]acetic Acid; 4-Fluorophenylmercaptoacetic Acid; (p-Fluorophenylthio)acetic Acid; 4-Fluorobenzenethiolacetic Acid; 4-Fluorothiophenol Acetic Acid; FPTA; 4-Fluorophenylthioacetic Acid; α-Carboxymethyl-4-fluorothioanisole
EINECS	206-370-5

Quality Control

Our (4-Fluorophenylthio)Acetic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.