Description

1-Bromo-4-(2-Fluoroethoxy)Benzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic combination of a bromo substituent and a fluoroethoxy side chain, enabling precise molecular construction for high-value applications. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate fluorine and aryl ether motifs into novel molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aryl ether linkage.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers to alter surface properties, chemical resistance, and thermal stability.
• Chemical Research: A valuable reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	1-Bromo-4-(2-Fluoroethoxy)Benzene
CAS No.	332-47-8
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	4-Bromo-1-(2-fluoroethoxy)benzene; p-Bromo(2-fluoroethoxy)benzene; 2-Fluoroethyl 4-bromophenyl ether; 1-Bromo-4-(2-fluoroethoxy)benzene; Benzene, 1-bromo-4-(2-fluoroethoxy)-; 4-Bromophenetole, 2-fluoro-; (2-Fluoroethoxy)-4-bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(2-Fluoroethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.