Description

4-Trifluoromethyl Thioanisole is a versatile organosulfur and organofluorine building block, recognized for its unique trifluoromethylthio (-SCF₃) functional group. This compound is highly valued in advanced chemical synthesis for its ability to impart desirable properties like enhanced lipophilicity and metabolic stability to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethylthioether moiety into drug candidates, potentially improving bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the -SCF₃ group can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, or functional polymers with tailored surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and nucleophilic substitutions to construct complex sulfur-containing fluorinated architectures.

Basic Information

Product Name	4-Trifluoromethyl Thioanisole
CAS No.	329-14-6
Molecular Formula	C₈H₇F₃S
Molecular Weight	192.20 g/mol
Synonyms	1-(Trifluoromethyl)-4-(methylthio)benzene; 4-(Methylthio)benzotrifluoride; p-(Trifluoromethyl)thioanisole; 4-Methylthiobenzotrifluoride; α,α,α-Trifluoro-4-(methylthio)toluene; 4-(Trifluoromethyl)phenyl methyl sulfide; p-Trifluoromethyl phenyl methyl sulfide
EINECS	206-343-5

Quality Control

Our production of 4-Trifluoromethyl Thioanisole adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.