Description

2-Amino-2-(3-Fluoro-Phenyl)-Propionic Acid is a fluorinated non-natural amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the unique combination of the amino acid backbone and the fluorine substituent, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in CNS and metabolic disorder research.
• Peptidomimetics & Drug Design: Used to incorporate fluorine into peptide analogs to enhance metabolic stability, bioavailability, and receptor binding affinity.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and plant growth regulators with improved efficacy.
• Chemical Biology & Proteomics: Employed in the synthesis of fluorinated amino acid probes for studying protein structure, function, and interactions.
• Material Science Research: Used in the synthesis of specialized polymers and advanced materials where fluorine incorporation is desired for specific properties.
• Academic & Contract Research: A valuable reagent for methodological development in asymmetric synthesis and fluorine chemistry at universities and CROs.

Basic Information

Product Name	2-Amino-2-(3-Fluoro-Phenyl)-Propionic Acid
CAS No.	328-81-4
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	3-Fluoro-DL-phenylalanine; DL-3-Fluorophenylalanine; (RS)-2-Amino-2-(3-fluorophenyl)propanoic acid; 2-Amino-2-(3-fluorophenyl)propionic acid; 3-Fluoro-α-methyl-DL-phenylalanine; α-Methyl-3-fluorophenylalanine; (R,S)-2-Amino-2-(3-fluorophenyl)propionic acid; 3-Fluorophenylalanine, α-methyl-
EINECS	206-329-4

Quality Control

Our 2-Amino-2-(3-Fluoro-Phenyl)-Propionic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.