Description

3,5-Bis(Trifluoromethyl)Bromobenzene is a high-value, multi-functional aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for introducing both halogen and fluorine functionalities in a single step, enabling the synthesis of complex molecules with tailored electronic and steric properties. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology, where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms to improve lipophilicity and membrane permeability of the active compounds.
• Ligand & Catalyst Development: Serves as a critical starting material for synthesizing sophisticated phosphine and N-heterocyclic carbene (NHC) ligands used in cross-coupling catalysis (e.g., Suzuki, Buchwald-Hartwig reactions).
• Advanced Material Precursor: Employed in the production of specialty polymers, liquid crystals, and organic light-emitting diodes (OLEDs) due to its ability to impart unique electronic characteristics and chemical resistance.
• Chemical Research & Development: A versatile reagent for exploring new reaction pathways in organofluorine chemistry and for constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Bromobenzene
CAS No.	328-70-1
Molecular Formula	C8H3BrF6
Molecular Weight	292.99 g/mol
Synonyms	1-Bromo-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)phenyl bromide; α,α,α,α',α',α'-Hexafluoro-3,5-bis(trifluoromethyl)bromobenzene; 3,5-Di(trifluoromethyl)bromobenzene; 3,5-Bis(trifluoromethyl)-1-bromobenzene; Bromo-3,5-bis(trifluoromethyl)benzene; (3,5-Bis(trifluoromethyl)phenyl)bromide
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Bromobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.