Description

2-Trifluoroacetamide-1,4-Dichlorobenzene is a specialized halogenated aromatic compound that serves as a versatile intermediate in advanced organic synthesis. Its molecular structure, featuring both a reactive trifluoroacetamide group and dichloro substitution, makes it a valuable building block for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated or chlorinated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the dichlorobenzene moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce the 2-trifluoroacetamide-1,4-dichlorobenzene fragment.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in both academic and industrial R&D laboratories.

Basic Information

Product Name	2-Trifluoroacetamide-1,4-Dichlorobenzene
CAS No.	328-11-0
Molecular Formula	C8H4Cl2F3NO
Molecular Weight	258.03 g/mol
Synonyms	1,4-Dichloro-2-(trifluoroacetamido)benzene; N-(2,5-Dichlorophenyl)-2,2,2-trifluoroacetamide; 2,5-Dichlorophenyltrifluoroacetamide; 2,2,2-Trifluoro-N-(2,5-dichlorophenyl)acetamide; α,α,α-Trifluoro-2',5'-dichloroacetanilide; 2',5'-Dichloro-α,α,α-trifluoroacetanilide; TFADCB
EINECS	Contact for details

Quality Control

Our 2-Trifluoroacetamide-1,4-Dichlorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.