Description

o-(4-Hydroxy-3-Iodophenyl)-3,5-Diiodo-D-Tyrosine is a highly iodinated derivative of the amino acid tyrosine, serving as a critical synthetic intermediate and reference standard. This compound is valued for its precise molecular structure, which is essential for research and development in advanced pharmaceutical synthesis. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of thyroid hormone analogs and other iodine-containing active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and precursor in metabolic pathway studies and enzyme inhibition research.
• Radiopharmaceutical Development: Serves as a non-radioactive precursor or cold standard for developing iodine-123 or iodine-131 labeled diagnostic and therapeutic agents.
• Fine Chemical Synthesis: Intermediate for creating specialized iodinated compounds used in material science and advanced organic synthesis.
• Diagnostic Reagent Manufacturing: Component in the development of chemical reagents and assay kits for clinical diagnostics.

Basic Information

Product Name	o-(4-Hydroxy-3-Iodophenyl)-3,5-Diiodo-D-Tyrosine
CAS No.	327-86-6
Molecular Formula	C15H11I3NO4
Molecular Weight	673.97 g/mol
Synonyms	3,5-Diiodo-D-thyronine; 3,5-Diiodothyronine; D-3,5-Diiodothyronine; 3,5-T2; 3,5-Diiodo-4-(4-hydroxyphenoxy)phenylalanine; o-(4-Hydroxy-3-iodophenyl)-3,5-diiodotyrosine; D-T2
EINECS	Contact for details

Quality Control

Our o-(4-Hydroxy-3-Iodophenyl)-3,5-Diiodo-D-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.