Description

4,4,4-Trifluoro-1-Phenyl-1,3-Butanedione is a versatile fluorinated β-diketone building block, prized for its unique trifluoromethyl group which imparts enhanced lipophilicity, metabolic stability, and electronic properties to target molecules. This compound is a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where fluorine substitution is strategically advantageous. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated heterocycles, ligands, and active pharmaceutical ingredients (APIs), leveraging the trifluoromethyl group to improve drug-like properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine atoms enhance biological activity and environmental stability.
• Coordination Chemistry & Catalysis: Serves as a chelating ligand for metals, forming stable complexes used in catalysis and material science applications.
• Advanced Material Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials for specialized performance characteristics.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel chemical entities.

Basic Information

Product Name	4,4,4-Trifluoro-1-Phenyl-1,3-Butanedione
CAS No.	326-06-7
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	1-Phenyl-4,4,4-trifluoro-1,3-butanedione; 4,4,4-Trifluoro-1-phenylbutane-1,3-dione; Benzoyltrifluoroacetone; 1,3-Butanedione, 4,4,4-trifluoro-1-phenyl-; TTA (Thenoyltrifluoroacetone analog); Phenyl trifluoroacetyl methane; α-Phenyl-β-trifluoroacetyl ethylene; 4,4,4-Trifluoro-1-phenyl-1,3-butanedione
EINECS	206-310-2

Quality Control

Our 4,4,4-Trifluoro-1-Phenyl-1,3-Butanedione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.