Description

4-Fluoro-1,1'-Biphenyl is a versatile fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom, enabling precise modifications to molecular structures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and liquid crystal materials sectors, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated biphenyl scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the fluorine atom can improve lipophilicity and target binding.
• Liquid Crystal Materials: Serves as a core structural unit in the production of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and host materials in OLED devices.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Research & Development: Fundamental reagent for exploring new fluorination methodologies and constructing novel aromatic compounds in academic and industrial R&D.

Basic Information

Product Name	4-Fluoro-1,1'-Biphenyl
CAS No.	324-74-3
Molecular Formula	C12H9F
Molecular Weight	172.20 g/mol
Synonyms	4-Fluorobiphenyl; p-Fluorobiphenyl; 1-Fluoro-4-phenylbenzene; 4-Fluorodiphenyl; (4-Fluorophenyl)benzene; 4-Phenylfluorobenzene; NSC 9235; Biphenyl, 4-fluoro-
EINECS	206-305-9

Quality Control

Our 4-Fluoro-1,1'-Biphenyl is produced under a stringent quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	70 - 74 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.