Description

10H-Phenothiazine-10-Propanamine,2-Chloro-N,n-Dimethyl-, 5-Oxide, Hydrochloride (1:1) is a high-purity phenothiazine derivative, a versatile chemical intermediate valued for its specific structural and reactive properties. This compound is critical for advanced synthesis in pharmaceutical research and fine chemical manufacturing, where precise molecular architecture is required. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with phenothiazine-based structures.
• Agrochemical Research: Used in the development and synthesis of novel crop protection agents and pesticides.
• Dye & Pigment Manufacturing: Serves as a precursor in the production of specialized dyes and organic pigments.
• Polymer Science: Employed as a monomer or additive in the synthesis of advanced polymers with specific electronic or optical properties.
• Chemical Research: A valuable reagent in organic synthesis for constructing complex heterocyclic systems and studying structure-activity relationships.
• Material Science: Investigated for use in the development of organic semiconductors and photoconductive materials.

Basic Information

Product Name	10H-Phenothiazine-10-Propanamine,2-Chloro-N,n-Dimethyl-, 5-Oxide, Hydrochloride (1:1)
CAS No.	316-07-4
Molecular Formula	C₁₇H₂₀Cl₂N₂OS
Molecular Weight	383.32 g/mol
Synonyms	Promethazine N-oxide hydrochloride; Promethazine sulfoxide hydrochloride; 10-(2-Dimethylaminopropyl)-2-chlorophenothiazine 5-oxide hydrochloride; 2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine 5-oxide hydrochloride; N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine 5-oxide hydrochloride; Promethazine 5-oxide hydrochloride; 316-07-4; EINECS 206-253-4
EINECS	206-253-4

Quality Control

Our 10H-Phenothiazine-10-Propanamine,2-Chloro-N,n-Dimethyl-, 5-Oxide, Hydrochloride (1:1) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.