Description

1-Fluoro-4-(Phenylsulphonyl)Benzene is a high-purity fluorinated aromatic sulfone compound, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a phenylsulfonyl group, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and fluorine-containing therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce sulfone and fluorine functionalities into polymer backbones, improving thermal stability and chemical resistance.
• Cross-Coupling Reactions: Acts as a reliable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Material Science Research: Utilized in academic and industrial R&D for creating novel organic semiconductors and advanced functional materials.

Basic Information

Product Name	1-Fluoro-4-(Phenylsulphonyl)Benzene
CAS No.	312-31-2
Molecular Formula	C12H9FO2S
Molecular Weight	236.26 g/mol
Synonyms	4-Fluorophenyl Phenyl Sulfone; p-Fluorophenyl Phenyl Sulfone; 1-Fluoro-4-(phenylsulfonyl)benzene; (4-Fluorophenyl)(phenyl)sulfone; 4-Fluorodiphenyl Sulfone; Phenyl 4-fluorophenyl sulfone; 312-31-2; NSC 403821
EINECS	206-227-9

Quality Control

Every batch of 1-Fluoro-4-(Phenylsulphonyl)Benzene is manufactured under strict quality management protocols. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, GC, and NMR. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.