Description

Doxapram CAS NO 309-29-5 is a potent central nervous system stimulant belonging to the class of analeptic agents. This compound is primarily valued for its ability to stimulate respiration, making it a critical pharmaceutical intermediate. It is essential for manufacturers in the pharmaceutical industry developing respiratory stimulants and analeptics. The product is supplied as a high-purity material suitable for further synthesis and formulation.

Application

• Primary use as a pharmaceutical active ingredient (API) in the manufacture of respiratory stimulants.
• Key intermediate in the synthesis of analeptic drugs used to treat respiratory depression.
• Utilized in clinical and research settings for studying central nervous system pharmacology.
• Component in veterinary medicine for respiratory support.
• Used in the development of controlled pharmaceutical formulations for precise dosing.
• Reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Doxapram
CAS No.	309-29-5
Molecular Formula	C24H30N2O2
Molecular Weight	378.51 g/mol
Synonyms	1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone; Dopram; Doxapram Hydrochloride (salt form); AHR-619; CC-885; RTG-001; Stimulex; Respirex
EINECS	206-186-5

Quality Control

Our Doxapram is manufactured under strict quality systems to ensure it meets the high standards required for pharmaceutical use. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting compliance with relevant pharmacopeial standards (such as USP/EP) are available upon request, providing full traceability and quality assurance for your supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.