Description

Benzamide, n-(2,5-Dioxo-3-Pyrrolidinyl)- CAS NO 305-86-2 is a high-purity chemical intermediate featuring a maleimide functional group. This compound is critical for the synthesis of advanced materials and pharmaceutical active ingredients, offering reliable reactivity for conjugation and cross-linking reactions. It is primarily sought by research institutions and manufacturers in the pharmaceutical, polymer, and specialty chemical industries for developing targeted therapies and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted drug delivery systems.
• Bioconjugation Reagent: Used to modify proteins, antibodies, and peptides via its maleimide group, which reacts selectively with thiols.
• Polymer Cross-Linking Agent: Employed in the production of thermosetting resins, adhesives, and coatings to enhance mechanical strength and thermal stability.
• Material Science Research: Serves as a precursor for developing functionalized surfaces, hydrogels, and smart materials.
• Diagnostic Reagent Synthesis: Utilized in creating labeled probes and assay components for biomedical diagnostics.
• Organic Synthesis: A versatile reagent for constructing heterocyclic compounds and complex molecular architectures in research chemistry.

Basic Information

Product Name	Benzamide, n-(2,5-Dioxo-3-Pyrrolidinyl)-
CAS No.	305-86-2
Molecular Formula	C11H8N2O3
Molecular Weight	216.19 g/mol
Synonyms	N-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-3-yl)benzamide; 3-Benzamidopyrrole-2,5-dione; 1H-Pyrrole-3-carboxamide, 2,5-dihydro-2,5-dioxo-N-phenyl-; N-(2,5-Dioxo-3-pyrrolidinyl)benzamide; 3-Benzamidomaleimide; Maleimide, 3-benzamido-; N-Phenylmaleamic acid imide
EINECS	206-170-2

Quality Control

Our Benzamide, n-(2,5-Dioxo-3-Pyrrolidinyl)- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.