Description

Boronic Acid, B-(2,3-Dichloro-5-Fluorophenyl)- is a high-purity, halogenated arylboronic acid derivative of significant interest in advanced organic synthesis. This compound is a critical building block for the construction of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing a biaryl motif.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boron reagent in palladium-catalyzed cross-coupling with organic halides to form carbon-carbon bonds.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and inhibitors for biochemical and pharmacological research.
• Catalyst Ligand Synthesis: Can be incorporated into the structure of sophisticated ligands used in homogeneous catalysis.

Basic Information

Product Name	Boronic Acid, B-(2,3-Dichloro-5-Fluorophenyl)-
CAS No.	2828433-43-6
Molecular Formula	C6H4BCl2FO2
Molecular Weight	208.82 g/mol
Synonyms	(2,3-Dichloro-5-fluorophenyl)boronic acid; 2,3-Dichloro-5-fluorobenzeneboronic acid; B-(2,3-Dichloro-5-fluorophenyl)boronic acid; 2,3-Dichloro-5-fluorophenyl-Boronic Acid; Boronic acid, B-(2,3-dichloro-5-fluorophenyl)-; (2,3-Dichloro-5-fluorophenyl)boronic acid pinacol ester (common derivative); 2,3-Dichloro-5-fluoro-benzeneboronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-(2,3-Dichloro-5-Fluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.