Description

(4R,4'R)-2,2'-(Cycloheptane-1,1-Diyl)Bis(4-Isopropyl-4,5-Dihydrooxazole) is a high-purity, chiral bis(oxazoline) ligand, a critical class of compounds in asymmetric synthesis. This product matters because it provides a sophisticated, structurally defined framework for creating highly enantioselective metal catalysts, enabling the production of single-isomer pharmaceutical intermediates and fine chemicals. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for copper, palladium, and other transition metals in enantioselective reactions such as cyclopropanations, Diels-Alder reactions, and conjugate additions.
• Pharmaceutical Intermediate Synthesis: For the stereocontrolled construction of complex molecular architectures in active pharmaceutical ingredient (API) development.
• Agrochemical Research: In the synthesis of chiral bioactive compounds for crop protection agents.
• Material Science: Potential use in the development of chiral polymers or frameworks with specific optical properties.
• Academic & Industrial R&D: A valuable tool for methodology development in organic and organometallic chemistry laboratories.

Basic Information

Product Name	(4R,4'R)-2,2'-(Cycloheptane-1,1-Diyl)Bis(4-Isopropyl-4,5-Dihydrooxazole)
CAS No.	2828432-03-5
Molecular Formula	C21H34N2O2
Molecular Weight	346.51 g/mol
Synonyms	(4R,4'R)-1,1'-Cycloheptanediylbis[4-(1-methylethyl)-4,5-dihydro-2-oxazole]; (R,R)-Cycloheptane-1,1-diylbis(4-isopropyl-4,5-dihydrooxazole); Chiral Bis(oxazoline) Ligand with Cycloheptane Backbone; (R,R)-H7Box-iPr; (R,R)-Cycloheptyl-Box-iPr; (4R,4'R)-2,2'-(1,1-Cycloheptanediyl)bis[4-(1-methylethyl)-2-oxazoline]; (R,R)-1,1'-Cycloheptylidenebis(4-isopropyl-2-oxazoline)
EINECS	Contact for details

Quality Control

Our (4R,4'R)-2,2'-(Cycloheptane-1,1-Diyl)Bis(4-Isopropyl-4,5-Dihydrooxazole) is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding catalytic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.