Description

Nh2-Peg-Rhb is a functionalized polyethylene glycol (PEG) derivative featuring a reactive amine (NH2) group and a Rhodamine B (Rhb) fluorophore. This bifunctional compound is engineered to serve as a versatile linker and labeling reagent, combining the biocompatibility and solubility of PEG with the fluorescent properties of RhB for advanced research and development. It is essential for scientists and engineers in the fields of bioconjugation, diagnostics, and materials science who require precise, traceable molecular constructs. The product is supplied under strict quality control to ensure batch-to-batch consistency for sensitive applications.

Application

• Bioconjugation and Protein Labeling: The amine group facilitates covalent attachment to carboxylates or other reactive sites on proteins, antibodies, and peptides, while the RhB fluorophore enables fluorescence detection and imaging.
• Polymer and Biomaterial Functionalization: Used to introduce fluorescent tags and reactive amine handles into hydrogels, nanoparticles, and other polymeric matrices for tracking and further chemical modification.
• Diagnostic Assay Development: Serves as a key component in the synthesis of fluorescent probes and sensors for in vitro diagnostic (IVD) kits and bioanalytical assays.
• Drug Delivery System Research: Incorporated into drug-polymer conjugates or nanocarriers to study biodistribution, cellular uptake, and release kinetics via fluorescence microscopy or flow cytometry.
• Cell Imaging and Tracking: Enables the fluorescent labeling of cells, organelles, or specific biomolecules for real-time visualization in live-cell or fixed-cell imaging studies.
• Surface Modification: Applied to coat and functionalize surfaces (e.g., glass, gold, polymers) to create biointerfaces with specific fluorescent and chemical properties.

Basic Information

Product Name	Nh2-Peg-Rhb
CAS No.	2757085-90-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details (Variable based on PEG chain length)
Synonyms	Amino-PEG-Rhodamine B
NH2-PEG-Rhodamine B
Rhodamine B-PEG-Amine
Amine-Polyethylene Glycol-RhB
RhB-PEG-NH2
PEGylated Rhodamine B amine
Fluorescent PEG amine derivative
EINECS	Contact for details

Quality Control

Every batch of Nh2-Peg-Rhb is manufactured and analyzed under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade chemicals. Critical parameters such as purity, degree of labeling, and functional group integrity are verified using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For optimal performance, use immediately after preparation of solutions.

Specification

Item	Specification
Appearance	Red to purple solid or viscous liquid
Identification (HPLC/MS)	Complies
Purity (HPLC)	≥ 95%
Amine Content (Titration)	Contact for details
Degree of Labeling (UV-Vis)	Contact for details
Moisture Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, water, common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.