Description

Carbinoxamine-D6 Maleate is a deuterium-labeled analog of the antihistamine carbinoxamine, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, such as LC-MS/MS. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and analytical laboratories engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development and validation.

Application

• Internal Standard for Bioanalysis: Critical for the precise quantification of carbinoxamine in complex biological matrices (e.g., plasma, serum, urine) using LC-MS/MS.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Method Development and Validation: Serves as a key component in establishing robust, reproducible, and regulatory-compliant analytical methods.
• Quality Control in Pharmaceutical Manufacturing: Used in impurity profiling and assay development to ensure batch-to-batch consistency and product purity.
• Forensic and Toxicology Analysis: Aids in the accurate identification and quantification of carbinoxamine in forensic investigations.

Basic Information

Product Name	Carbinoxamine-D6 Maleate
CAS No.	2747914-08-3
Molecular Formula	C20H19D6ClN2O4
Molecular Weight	401.90 g/mol (for deuterated form)
Synonyms	Carbinoxamine-d6 Maleate; 2-[(4-Chlorophenyl)(pyridin-2-yl)methoxy]-N,N-dimethylethanamine-d6 Maleate; (+-)-Carbinoxamine-d6 Maleate; Allergefon-d6 Maleate; Carbinoxamine (phenyl-d5, N-methyl-d) Maleate; Histex-d6 Maleate; Clistin-d6 Maleate; Carbinoxamine D6 (Maleate Salt)
EINECS	Contact for details

Quality Control

Every batch of Carbinoxamine-D6 Maleate is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We guarantee high chemical and isotopic purity, confirmed by advanced techniques including NMR (1H, 13C), HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and other critical specifications to support your regulatory submissions and ensure data integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.