Description

Zamocillin-D4 is a deuterated analog of the β-lactam antibiotic, Zamocillin, specifically designed for use as an internal standard in advanced analytical chemistry. This high-purity compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS) analyses. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and quality control departments for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS quantification of Zamocillin in biological matrices (plasma, serum, tissue).
• Method Development and Validation in pharmaceutical bioanalysis to meet regulatory guidelines (FDA, EMA).
• Metabolite Profiling and Identification studies in drug discovery and development.
• Pharmacokinetic (PK) and Toxicokinetic (TK) studies to track drug absorption, distribution, metabolism, and excretion.
• Quality Control and Assurance testing for antibiotic potency and purity in manufacturing.
• Stability-indicating assays to monitor drug degradation under various conditions.

Basic Information

Product Name	Zamocillin-D4
CAS No.	2673270-36-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Zamocillin-d4; Deuterated Zamocillin; [²H₄]-Zamocillin; Zamocillin (D4); Zamocillin Internal Standard; (2S,5R,6R)-6-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid-d4; Amoxicillin-d4 (related analog)
EINECS	Contact for details

Quality Control

Our Zamocillin-D4 CAS NO 2673270-36-3 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, purity (by HPLC), isotopic purity (by MS), and residual solvents. We adhere to relevant industry standards for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and must be handled under inert, dry conditions to maintain stability and purity. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.