Description

(2-Amino-3,5-Dichloro-6-Fluorophenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique halogenated and aminated aromatic structure makes it an indispensable intermediate for constructing complex molecules, particularly in the pharmaceutical sector. This compound is primarily sought after by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Utilized as a molecular probe or linker in bioconjugation and the study of protein interactions due to its boronic acid moiety.
• Catalyst Ligand Development: Acts as a precursor for creating specialized ligands used in homogeneous catalysis for fine chemical synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated arylboronic acids.

Basic Information

Product Name	(2-Amino-3,5-Dichloro-6-Fluorophenyl)Boronic Acid
CAS No.	2638502-53-9
Molecular Formula	C6H5BCl2FNO2
Molecular Weight	223.83 g/mol
Synonyms	2-Amino-3,5-dichloro-6-fluorophenylboronic acid; (2-Amino-3,5-dichloro-6-fluorophenyl)boronic acid; 3,5-Dichloro-2-amino-6-fluorophenylboronic acid; Boronic acid, B-(2-amino-3,5-dichloro-6-fluorophenyl)-; 2638502-53-9; 2-Amino-3,5-dichloro-6-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of (2-Amino-3,5-Dichloro-6-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.