Description

(S)-4-Benzyl-2-(2-Chloro-6-(Diphenylphosphino)Phenyl)-4,5-Dihydrooxazole is a chiral, P,N-bidentate ligand, a critical class of organocatalysts and auxiliaries in modern synthetic chemistry. Its value lies in enabling highly enantioselective transformations, which are essential for producing single-isomer pharmaceuticals and fine chemicals with high purity and efficacy. This compound is primarily needed by research institutions and industrial R&D departments focused on asymmetric catalysis, process chemistry, and the development of novel active pharmaceutical ingredients (APIs).

Application

• As a chiral ligand in asymmetric transition metal catalysis, such as hydrogenation, cross-coupling, and hydroformylation reactions.
• As a key component in the synthesis of enantiomerically pure pharmaceutical intermediates and active ingredients.
• For use in academic and industrial research to develop new catalytic methodologies for complex molecule construction.
• As a precursor or auxiliary in the preparation of other specialized chiral catalysts and ligands.
• In process chemistry for the scale-up and optimization of enantioselective synthetic routes.

Basic Information

Product Name	(S)-4-Benzyl-2-(2-Chloro-6-(Diphenylphosphino)Phenyl)-4,5-Dihydrooxazole
CAS No.	2634687-64-0
Molecular Formula	C28H23ClNOP
Molecular Weight	455.91 g/mol
Synonyms	(S)-4-Benzyl-2-(2-chloro-6-(diphenylphosphanyl)phenyl)-4,5-dihydrooxazole; (S)-2-(2-Chloro-6-(diphenylphosphino)phenyl)-4-benzyl-4,5-dihydrooxazole; (S)-4-Benzyl-2-(2-chloro-6-(diphenylphosphino)phenyl)-2-oxazoline; (S)-4-Benzyl-2-(2-chloro-6-(diphenylphosphanyl)phenyl)-2-oxazoline; (S)-4-Benzyl-2-(2-chloro-6-(diphenylphosphanyl)phenyl)-4,5-dihydro-1,3-oxazole; (S)-4-Benzyl-2-(2-chloro-6-(diphenylphosphino)phenyl)-4,5-dihydro-1,3-oxazole; (S)-4-Benzyl-2-(2-chloro-6-(diphenylphosphanyl)phenyl)-4,5-dihydrooxazole CAS 2634687-64-0
EINECS	Contact for details

Quality Control

Our (S)-4-Benzyl-2-(2-Chloro-6-(Diphenylphosphino)Phenyl)-4,5-Dihydrooxazole is manufactured under strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and identity confirmation. We adhere to ISO 9001 quality management standards, and our analytical methods are validated to meet the rigorous demands of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.